The Pleiades (/ˈpliː.ədiːz, ˈpleɪ-, ˈplaɪ-/), also known as The Seven Sisters, Messier 45, and other names by different cultures, is an asterism and an open star cluster containing middle-aged, hot B-type stars in the north-west of the constellation Taurus. It is among the star clusters nearest to Earth, it is the nearest Messier object to Earth, and is the cluster most obvious to the naked eye in the night sky.

The cluster is dominated by hot blue and luminous stars that have formed within the last 100 million years. Reflection nebulae around the brightest stars were once thought to be left over material from their formation, but are now considered likely to be an unrelated dust cloud in the interstellar medium through which the stars are currently passing.[9]

Computer simulations have shown that the Pleiades were probably formed from a compact configuration that resembled the Orion Nebula.[10] Astronomers estimate that the cluster will survive for about another 250 million years, after which it will disperse due to gravitational interactions with its galactic neighborhood.[11]

Together with the open star cluster of the Hyades, the Pleiades form the Golden Gate of the Ecliptic.

The name of the Pleiades comes from Ancient Greek, Πλειάδες. It probably derives from plein ("to sail") because of the cluster's importance in delimiting the sailing season in the Mediterranean Sea: "the season of navigation began with their heliacal rising". However, in mythology the name was used for the Pleiades, seven divine sisters, the name supposedly deriving from that of their mother Pleione and effectively meaning "daughters of Pleione". In reality, the name of the star cluster almost certainly came first, and Pleione was invented to explain it.

Galileo Galilei was the first astronomer to view the Pleiades through a telescope. He thereby discovered that the cluster contains many stars too dim to be seen with the naked eye. He published his observations, including a sketch of the Pleiades showing 36 stars, in his treatise Sidereus Nuncius in March 1610.

The Pleiades have long been known to be a physically related group of stars rather than any chance alignment. John Michell calculated in 1767 that the probability of a chance alignment of so many bright stars was only 1 in 500,000, and so surmised that the Pleiades and many other clusters of stars must be physically related. When studies were first made of the stars' proper motions, it was found that they are all moving in the same direction across the sky, at the same rate, further demonstrating that they were related.

Charles Messier measured the position of the cluster and included it as M45 in his catalogue of comet-like objects, published in 1771. Along with the Orion Nebula and the Praesepe cluster, Messier's inclusion of the Pleiades has been noted as curious, as most of Messier's objects were much fainter and more easily confused with comets—something that seems scarcely possible for the Pleiades. One possibility is that Messier simply wanted to have a larger catalogue than his scientific rival Lacaille, whose 1755 catalogue contained 42 objects, and so he added some bright, well-known objects to boost his list.

Edme-Sébastien Jeaurat then drew in 1782 a map of 64 stars of the Pleiades from his observations in 1779, which he published in 1786.